SCP-DM

Human pluripotent stem cell differentiation medium kit for the rapid manufacture of Schwann cell precursors by end users.

Reach Out For Pricing

SCP-DM is a human pluripotent stem cell differentiation (hPSC) kit that allows researchers to rapidly manufacture Schwann Cell Precursors (SCPs) in a scalable manner within 9 days using the hPSC lines they already have. This kit is suitable for pharmaceutical companies, academic research settings, and other research facilities for your SCP needs including Charcot-Marie-Tooth syndrome or diabetic neuropathy.

Pluripotent stem cells are patterned towards “primal ectoderm” in 24 hours, which can be further patterned into HOXB1 expressing neural crest and subsequently differentiated into SCPs characterized by SOX10 and S100b expression with up to 90% efficiency. Scale bar = 100 um.

TECHNOLOGY

PRODUCTS

Successful Production of hiPSC-Derived Schwann Cell Precursors

SCP-DM requires only standard laboratory equipment and is designed for use by researchers of all skill levels. The easy-to-complete production of human pluripotent stem cell-derived Schwann cell precursors is part of a complementary suite of Schwann cell precursor products for a variety of research interests.

SCP-MM: for the rapid maturation of of SCPs into myelinating Schwann cells
RealSCP™: cryopreserved Schwann cell precursors for off-the-shelf use

Anatomic's SCP-DM was developed to put the power of your research back into your own hands. User-friendly, high-quality and researcher-focused, our human pluripotent stem cell differentiation kit allows your lab to consistently innovate, experiment and discover new pain treatments faster and more reliably than ever before.

Anatomic Produces a Highly Pure Population in Only 9 Days

By allowing neuroscience researchers to manufacture Schwann cell precursors, entire research teams can develop new workflows, streamline processes and focus on innovation and results.

Fast

SCP-DM produces differentiation of human pluripotent stem cells into Schwann cell precursors faster than ever in just 9 days

Effective

Manufactures between 10 - 30 million Schwann Cell Precursors with 80% purity for SOX10 and S100b.

Quality Controlled

To eliminate variability, SCP-DM uses serum-free, chemically defined media and has been validated for use downstream from multiple defined systems for the undifferentiated culture of hiPSCs.

Anatomic Produces a Highly Pure Population in Only 9 Days

The SCP-DM Kit rapidly generates human Schwann cell precursors in just 9 days. Starting from ectoderm within 24 hours, cells are guided through a HOXB1+ neural crest stage before becoming SOX10+/S100b+ Schwann cell precursors. SCP-DM supports co-culture studies with motor or sensory neurons and is used to model demyelinating neuropathies such as CMT1A.

Proven in a Number of Assays

We've performed extensive assay development for a number of techniques so that your first experiments will run smoothly. Without the need for extensive optimization, researchers can focus on discovery and innovation.