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SCP-DM

Human pluripotent stem cell differentiation medium kit for the rapid manufacture of Schwann cell precursors by end users.

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SCP-DM is a human pluripotent stem cell differentiation (hPSC) kit that allows researchers to rapidly manufacture Schwann Cell Precursors (SCPs) in a scalable manner within 9 days using the hPSC lines they already have. This kit is suitable for pharmaceutical companies, academic research settings, and other research facilities for your SCP needs including Charcot-Marie-Tooth syndrome or diabetic neuropathy.

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Pluripotent stem cells are patterned towards “primal ectoderm” in 24 hours, which can be further patterned into HOXB1 expressing neural crest and subsequently differentiated into SCPs characterized by SOX10 and S100b expression with up to 90% efficiency. Scale bar = 100 um.

TECHNOLOGY
PRODUCTS
Anatomic Produces a Highly Pure Population in Only 9 Days

​By allowing neuroscience researchers to manufacture Schwann cell precursors, entire research teams can develop new workflows, streamline processes and focus on innovation and results.

Fast

SCP-DM produces differentiation of human pluripotent stem cells into Schwann cell precursors faster than ever in just 9 days

Effective

Manufactures between 10 - 30 million Schwann Cell Precursors with 80% purity for SOX10 and S100b.

Quality Controlled

To eliminate variability, SCP-DM uses serum-free, chemically defined media and has been validated for use downstream from multiple defined systems for the undifferentiated culture of hiPSCs.

Proven in a Number of Assays

We've performed extensive assay development for a number of techniques so that your first experiments will run smoothly.  Without the need for extensive optimization, researchers can focus on discovery and innovation.

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Alignment

Myelination

qPCR

Rapid Maturation

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Optimized for Screening

MEA

Immunocytochemistry

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