SCP-DM is a human pluripotent stem cell differentiation (hPSC) kit that allows researchers to rapidly manufacture Schwann Cell Precursors (SCPs) in a scalable manner within 9 days using the hPSC lines they already have. This kit is suitable for pharmaceutical companies, academic research settings, and other research facilities for your SCP needs including Charcot-Marie-Tooth syndrome or diabetic neuropathy.
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Pluripotent stem cells are patterned towards “primal ectoderm” in 24 hours, which can be further patterned into HOXB1 expressing neural crest and subsequently differentiated into SCPs characterized by SOX10 and S100b expression with up to 90% efficiency. Scale bar = 100 um.
Anatomic Produces a Highly Pure Population in Only 9 Days
​By allowing neuroscience researchers to manufacture Schwann cell precursors, entire research teams can develop new workflows, streamline processes and focus on innovation and results.
Fast
SCP-DM produces differentiation of human pluripotent stem cells into Schwann cell precursors faster than ever in just 9 days
Effective
Manufactures between 10 - 30 million Schwann Cell Precursors with 80% purity for SOX10 and S100b.
Quality Controlled
To eliminate variability, SCP-DM uses serum-free, chemically defined media and has been validated for use downstream from multiple defined systems for the undifferentiated culture of hiPSCs.
Proven in a Number of Assays
We've performed extensive assay development for a number of techniques so that your first experiments will run smoothly. Without the need for extensive optimization, researchers can focus on discovery and innovation.
Alignment
Myelination
qPCR
Rapid Maturation
Optimized for Screening
MEA
Immunocytochemistry
SCP-DM Resources
Find product manuals and other useful documentation for this product.
SCP-DM Quick Guide
Version 1.0​
Reach out for more information on your assays of interest: support@anatomic.com