Moto-DM

Human pluripotent stem cell differentiation medium for the rapid manufacture of motor neurons by end users.

Moto-DM is a human pluripotent stem cell differentiation (hiPSC) kit that allows researchers to rapidly manufacture motor neurons at the scale. Suitable for pharmaceutical companies and academic labs with their own wild-type and disease hiPSC lines, this differentiation media provides the ability for ALS, CMT, and neuromuscular disease modeling.

Anatomic's breakthrough in producing ectoderm from hiPSCs within 24 hours provides near-immediate access to engineering neuron diversity unique to the nervous system. Moto-DM builds upon these findings to produce a highly pure population of immature motor neurons within only seven days.

Streamline Your Research

By allowing neuroscience researchers to manufacture motor neurons, entire research teams can develop new workflows, streamline processes and focus on innovation and results.

Fast

Moto-DM produces differentiation of human pluripotent stem cells into motor neurons faster than ever, with a pure population of immature motor neurons in seven days.

Effective

Manufactures up to 10 million motor neurons with 75% purity for HB9, ISL1, TUJ1 and CHAT.

Quality Controlled

To eliminate variability, Moto-DM uses serum-free, chemically defined media and has been validated for use downstream from multiple defined systems for the undifferentiated culture of hiPSCs.

Successful Production of hiPSC-Derived Motor Neurons

Moto-DM requires only standard laboratory equipment and is designed for use by researchers of all skill levels. The easy-to-complete production of human pluripotent stem cell-derived motor neurons is part of a complementary suite of motor neuron products for a variety of research interests.

Moto-MM: for the rapid maturation of ion channels and electrophysical activity
RealMOTO™: cryopreserved motor neurons for off-the-shelf use

Anatomic's Moto-DM was developed to put the power of your research back into your own hands. User-friendly, high-quality and researcher-focused, our human pluripotent stem cell differentiation kit allows your lab to consistently innovate, experiment and discover new pain treatments faster and more reliably than ever before.

Proven in a Number of Assays

We've performed extensive assay development for a number of techniques so that your first experiments will run smoothly. Without the need for extensive optimization, researchers can focus on discovery and innovation.

MEA

NMJ Co-Culture

Calcium Imaging