MELO-DM

Human pluripotent stem cell differentiation medium kit for the rapid manufacture of melanocytes by end users.

The Anatomic Primal Ectoderm Platform is a “shortcut to shortcuts” allowing the rapid directed differentiation of human melanocytes from pluripotent stem cells in only 7 days. Pluripotent stem cells are patterned towards ‘primal ectoderm’ in 24 hours which are further patterned towards HOXB1 expressing neural create and terminally differentiated into melanocytes expressing MITF and SOX10 with up to 85% efficiency.

PRODUCTS

High Efficiency and Yield

Our revolutionary MELO-DM kit exhibit an outstanding efficiency of up to 85% in generating SOX10+/MITF+ melanocytes. Researchers can also manufacture up to 10 million cells. This remarkable level of efficiency and yield ensures a highly enriched population of functional melanocytes with the essential markers required for their proper identification and characterization.

Such high efficiency not only reduces the time and effort required for generating melanocytes but also guarantees a reliable and consistent supply of cells for various research applications.

Rapid Differentiation Protocol

Anatomic's MELO-DM kit offers a groundbreaking advancement in melanocyte research by providing a simplified and efficient 7-day protocol for their generation. This streamlined process allows researchers to generate high-quality melanocytes from human iPSCs in a significantly shorter timeframe compared to traditional methods.

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Pigmentation In Only 7 days

Anatomics' MELO-DM showcases pigment production visible to the naked eye in as little as 7 days of maturation. If your drug screen readout is pigmentation, the effects will be obvious in as little as 7 days post-thaw! With MELO-DM, researchers can confidently delve into the intricacies of melanocyte biology, pigmentation disorders, and melanoma while knowing they are working with a highly efficient and reliable cell population.

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MELO-DM Resources

Find product manuals and other useful documentation for this product.

Drastically Accelerated Directed Differentiation of Human Induced Pluripotent Stem Cells into Melanocytes for Phenotypic Screening

MELO-DM Protocols

MELO-DM Quick Guide

Version 1.0

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